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. 2022 Aug 5;13:938794. doi: 10.3389/fneur.2022.938794

Table 2.

Risk of first stroke (total and subtypes) associated with serum albumin-corrected calcium levels*.

Albumin-corrected
calcium, mg/dL
Cases/controls Model 1 Model 2
OR (95% CI) P OR (95% CI) P
First stroke
Tertiles
T1 (<8.7) 440/397 1.35 (1.11, 1.65) 0.003 1.37 (1.10, 1.70) 0.005
T2 (8.7–9.1) 379/457 Ref. Ref.
T3 (≥9.1) 436/401 1.33 (1.09, 1.62) 0.005 1.30 (1.04, 1.62) 0.020
Ischemic stroke
Tertiles
T1 (<8.7) 376/342 1.35 (1.09, 1.67) 0.006 1.41 (1.11, 1.79) 0.005
T2 (8.7–9.1) 327/396 Ref. Ref.
T3 (≥9.1) 376/341 1.36 (1.10, 1.69) 0.005 1.34 (1.05, 1.71) 0.017
Hemorrhagic stroke
Tertiles
T1 (<8.7) 62/53 1.43 (0.82, 2.48) 0.210 1.22 (0.65, 2.30) 0.535
T2 (8.7–9.1) 51/60 Ref. Ref.
T3 (≥9.1) 58/58 1.17 (0.70, 1.95) 0.561 0.87 (0.46, 1.63) 0.661
*

Model 1 is conditioned on the matching factors of age, sex, and village.

Model 2 is conditioned on the matching factors of age, sex and village, and adjusted for BMI, SBP, DBP, smoking status, drinking status, labor intensity, total cholesterol, triglycerides, HDL-C, fasting glucose, total homocysteine, eGFR, phosphate, 25(OH)D3, magnesium, antihypertensive drugs, glucose-lowering drugs, lipid-lowering drugs, antiplatelet drugs.