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. 2022 Aug 5;9:918996. doi: 10.3389/fcvm.2022.918996

Table 3.

Association of the NAPAIR with all-cause and cardiovascular disease mortality in US adults.

Mortality outcome Death/No. Weighted death (%) Hazard ratio (95% CI)
Model 1a Model 2b Model 3c
All causes
NAPAIR
<0.17 347/1,884 4,912,315 (11.1) 1[Reference] 1[Reference] 1[Reference]
≥0.17 292/1,806 4,184,788 (10.1) 1.53 (1.31–1.80) 1.60 (1.35–1.89) 1.46 (1.22–1.75)
Per 0.1 increase NA NA 1.24 (1.15–1.33) 1.23 (1.14–1.33) 1.15 (1.06–1.26)
Cardiovascular death
NAPAIR
<0.17 58/1,884 849,221 (1.9) 1[Reference] 1[Reference] 1[Reference]
≥0.17 56/1,806 721,872 (1.7) 1.77 (1.22–2.56) 1.87 (1.27–2.76) 1.58 (1.03–2.41)
Per 0.1 increase NA NA 1.21 (1.01–1.45) 1.21 (1.01–1.44) 1.09 (0.88–1.34)

NAPAIR, Nighttime to all-day physical activity intensity ratio.

a

Adjusted for age (as a continuous variable).

b

Additionally adjusted for sex, race/ethnicity, education attainment, marital status, and family poverty income ratio (as a continuous variable).

c

Additionally adjusted for body mass index (as a continuous variable), health status, smoking status, diabetes, hypercholesterolemia, hypercholesterolemia, and overall average physical activity intensity (as a continuous variable).