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. 2022 Aug 5;13:926318. doi: 10.3389/fimmu.2022.926318

Figure 3.

Figure 3

Lack of correlation between cytokine+ T-cell and humoral responses in MS patients treated with anti-CD20. Spearman’s correlation between IFNγ+ (green), IL-2+ (red) and IFNγ+/IL-2+ (yellow) T-cell response and the relative anti-RBD IgG OD values of aCD20-MS patients (n=42). r coefficient and P value are included for each correlation. The bold, continuous line indicates the regression line and the vertical dotted line highlights limit of sensitivity for antibody titers.