Table 2.
Risk factors analysis of PD-L1 expression in EGFR-mutated patients.
| Variables | PD-L1 expression | p-value | ||
|---|---|---|---|---|
| Negative (<1%) | Medium (1–49%) | High (≥50%) | ||
| Gender | 0.9213 | |||
| Female | 38 (66.67%) | 27 (62.80%) | 9 (64.29%) | |
| Male | 19 (33.33%) | 16 (37.21%) | 5 (35.71%) | |
| Age | 0.6615 | |||
| Age<65 | 40 (70.18%) | 28 (65.12%) | 7 (50.00%) | |
| 65≤Age<75 | 13 (22.81%) | 10 (23.26%) | 5 (35.71%) | |
| Age≥75 | 4 (7.02%) | 5 (11.63%) | 2 (14.29%) | |
| Smoking history | 0.6538 | |||
| Ever | 29 (50.88%) | 19 (44.19%) | 8 (57.14%) | |
| Never | 28 (49.12%) | 24 (55.81%) | 6 (42.86%) | |
| Prior lines of therapy | 0.5956 | |||
| 0 | 1 (1.75%) | 3 (6.98%) | 1 (7.14%) | |
| 1–2 | 34 (59.65%) | 27 (62.79%) | 7 (50.00%) | |
| ≥3 | 22 (38.60%) | 13 (30.23%) | 6 (42.86%) | |
| EGFR status | 0.1711 | |||
| Major | 41 (73.21%) | 27 (62.79%) | 8 (61.54%) | |
| Rare | 7 (12.50%) | 10 (23.26%) | 5 (38.46%) | |
| Others | 8 (14.29%) | 6 (13.95%) | 0 (0.00%) | |
| T790M status | 0.0825 | |||
| Positive | 21 (38.18%) | 13 (30.95%) | 1 (7.14%) | |
| Negative | 34 (61.82%) | 29 (69.05%) | 13 (92.86%) | |