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. 2022 Aug 5;13:931718. doi: 10.3389/fimmu.2022.931718

Table 2.

Risk factors analysis of PD-L1 expression in EGFR-mutated patients.

Variables PD-L1 expression p-value
Negative (<1%) Medium (1–49%) High (≥50%)
Gender 0.9213
 Female 38 (66.67%) 27 (62.80%) 9 (64.29%)
 Male 19 (33.33%) 16 (37.21%) 5 (35.71%)
Age 0.6615
 Age<65 40 (70.18%) 28 (65.12%) 7 (50.00%)
 65≤Age<75 13 (22.81%) 10 (23.26%) 5 (35.71%)
 Age≥75 4 (7.02%) 5 (11.63%) 2 (14.29%)
Smoking history 0.6538
 Ever 29 (50.88%) 19 (44.19%) 8 (57.14%)
 Never 28 (49.12%) 24 (55.81%) 6 (42.86%)
Prior lines of therapy 0.5956
 0 1 (1.75%) 3 (6.98%) 1 (7.14%)
 1–2 34 (59.65%) 27 (62.79%) 7 (50.00%)
 ≥3 22 (38.60%) 13 (30.23%) 6 (42.86%)
EGFR status 0.1711
 Major 41 (73.21%) 27 (62.79%) 8 (61.54%)
 Rare 7 (12.50%) 10 (23.26%) 5 (38.46%)
 Others 8 (14.29%) 6 (13.95%) 0 (0.00%)
T790M status 0.0825
 Positive 21 (38.18%) 13 (30.95%) 1 (7.14%)
 Negative 34 (61.82%) 29 (69.05%) 13 (92.86%)