Table 3.
Univariate and multivariate analyses of each factor’s ability in predicting PFS for 114 EGFR-mutated patients receiving ICIs.
Variables | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | p | |
Gender | 0.752 | 0.343 | ||
Female | Reference | Reference | ||
Male | 1.067 (0.705–1.615) | 1.235 (0.798–1.910) | ||
Age | 0.578 | 0.490 | ||
Age<65 | Reference | Reference | ||
65≤ Age <75 | 0.997 (0.623–1.576) | 0.968 | 1.043 (0.648–1.678) | 0.862 |
Age≥75 | 0.683 (0.373–1.251) | 0.255 | 0.648 (0.308–1.365) | 0.254 |
Smoking history | 0.172 | 0.150 | ||
Ever | Reference | Reference | ||
Never | 1.304 (0.882–1.928) | 1.359 (0.895–2.065) | ||
Treatment | 0.799 | 0.930 | ||
Monotherapy | Reference | Reference | ||
Combination | 1.075 (0.602–1.920) | 1.027 (0.572–1.841) |