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. 2022 Aug 5;13:941608. doi: 10.3389/fimmu.2022.941608

Figure 2.

Figure 2

Correlation analysis between TIM-4 and EMT markers in patients with CRS. (A-C) The expression of the EMT markers E-cadherin and α-SMA in different human sinonasal mucosal tissues. (A) Images show the representative immunostaining of E-cadherin and α-SMA in the sinonasal mucosa of healthy individuals and CRSsNP, E-CRSwNP, and NE-CRSwNP patients by IHC (control group: n=8; CRSsNP group: n=11; E-CRSwNP group: n=11; NE-CRSwNP group: n=9). (B, C) Quantitative summary of the intensity of E-cadherin (B) and α-SMA (C) in the human sinonasal mucosa. (D, E) The correlation between TIM-4 and EMT markers E-cadherin and α-SMA. (F-H) The correlation between TIM-4 and the clinical parameters of VAS score, Lund–Mackay score and Lund–Kennedy score. The Pearson correlation test was used, and r2 represents the coefficient of determination. All of the above representative pictures are shown at a magnification of 400×. Bars show the mean ± SD. **P<0.01,***P<0.001.