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. 2022 Aug 5;13:929091. doi: 10.3389/fendo.2022.929091

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Copyright © 2022 Garcia-Alvarez, Hernando, Carmona-Alonso and Capdevila

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of the most relevant information about biomarkers and immunotherapy efficacy in clinical trials in thyroid neoplasms. TAM, tumor-associated macrophage; MDSC, myeloid-derived suppressor cell; PD-L1^T, PD-L1 membranous expression in tumor cells; TMB, tumor mutational burden; ORR, overall response rate; Mono-IO, immunotherapy monotherapy; IO-Combo, immunotherapy in combination with immunotherapy; MKI + IO, multikinase inhibitor in combination with immunotherapy.