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. 2022 Aug 5;12:923043. doi: 10.3389/fonc.2022.923043

Table 5.

Association between benign renal epithelial iron levels and RCC patient clinical features.

Benign renal epithelium iron level (mean H-Score/SE)
All RCC ccRCC Non-ccRCC
Age, years ≤ 60>60p-value 0.2/0.11/0.70.013 0.3/0.11.1/0.90.33 0/00.4/0.20.007
Gender MaleFemalep-value 0.2/0.11.2/0.90.58 0.2/0.11.6/1.20.73 0.3/0.10/00.045
Race CaucasianAAp-value 0.5/0.41.1/1.0.38 0.6/0.52.3/2.30.31 0.2/0.10.3/0.21.00
Body mass index, kg/m2 <30≥ 30p-value 0.2/0.11.2/0.80.32 0.2/0.11.3/1.00.27 0.2/0.10.3/0.20.82
Smoking history NeverAnyp-value 0.9/0.80.3/0.10.13 1.1/1.00.4/0.20.15 0.2/0.10.2/0.10.48
Smoking pack years 0≤ 30>30p-value 0.9/0.80.3/0.20.4/0.30.42 1.1/1.00.4/0.20.5/0.40.39 0.2/0.10.2/0.10/00.63
Iron supplementation NoYesp-value 0.7/0.50.3/0.3.92 0.8/0.60.4/0.40.64 0.3/0.10/00.38
Anemia NoYesp-value 0.4/0.21.8/1.60.80 0.4/0.22.3/2.10.99 0.4/0.20.1/0.10.46
Microcytic anemia NoYesp-value 0.3/0.10.1/0.10.72 0.4/0.20.1/0.10.88 0.3/0.10/00.46
Hemoglobin, g/dl < 13.3≥ 13.3p-value 1.5/1.40.4/0.20.75 1.9/1.80.4/0.30.65 0.2/0.10.4/0.20.86
Hypertension NoYesp-value 1.3/1.30.3/0.10.22 1.6/1.60.3/0.2.55 0/00.4/0.2.24
Presence of metastasis NoYesp-value 0.6/0.40.4/0.20.89 0.7/0.50.4/0.30.36 0.2/0.10/00.45

AA, African American; SE, standard error. Bold p-values signify statistical significance.