Skip to main content
. 2022 Jul 16;3:100119. doi: 10.1016/j.crphar.2022.100119

Table 5.

Indole-based compounds targeting DNA replication machinery.

Sr. No. Compound Structure % Inhibition/IC50 Ref.
24. 3-((1-Oxoindolin-2-ylidene)methyl)phenyl benzoate Image 24 NA (Kumar et al., 2012)
25. 2-(1H-indol-3-yl) ethylthiourea Image 25 72.6 ​± ​1.2 ​μg/mL (Sanna et al., 2018)
26. 3-(1-Benzyl-5-chloro-2-(ethoxycarbonyl)-4-(trifluoromethyl)-1H-indol-3-yl) propanoic acid Image 26 86.6 ​μM (Singh et al., 2020)
27. Indole-3-acetic acid-based inhibitor Image 27 3.9 ​μM (Dewangan et al., 2021)
28. Tetracyclic indole derivatives Image 28 NA (Yadav et al., 2015)
29. 4-((3-Acetyl-1-benzyl-2-methyl-1H-indol-5-yl) oxy) butanoic acid Image 29 150 ​μM (Sharma et al., 2018)
30. (1-(1-Benzyl-5-((1-(4- bromophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2-methyl-1H-indol-3-yl) ethanone) Image 30 6.79 ​μM (Sharma et al., 2019)