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. 2022 Aug 4;9(3):e33754. doi: 10.2196/33754

Table 8.

Model for anxiety (cumulative link mixed-effects model) and negative affect (linear mixed-effects model) with variance inflation factor–reduced heart rate variability features derived from beat-to-beat interval data during normal work hours of 8 AM to 6 PMa.

Predictors Positive affectb Negative affectc Anxietyd

Standardized β Standardized 95% CI P value IRRe 95% CI P value ORf (95% CI) P value
Intercept −.01 −0.07 to 0.05 <.001 6.32 6.22 to 6.43 <.001 g
MRRIh −.15 −0.17 to −0.12 <.001 0.99 −0.06 to −0.004 .06 0.90 (0.83 to 0.97) .004 i
LFj/HFk −.08 −0.10 to −0.07 <.001 1.00 −0.03 to 0.01 .88 0.92 (0.87 to 0.97) .002 i
VLFl .12 0.09 to 0.15 <.001 1.04 0.06 to 0.12 <.001 1.51 (1.39 to 1.65) <.001 i
Triangular index .00 −0.02 to 0.02 .91 0.98 −0.08 to −0.03 .001 0.91 (0.85 to 0.97) .005 i
SDANNm −.03 −0.05 to −0.01 .002 0.98 −0.07 to 0.03 <.001 0.76 (0.72 to 0.81) <.001 i

aModels fit on 14,695 observations from 657 participants. P values <.05 are highlighted in italics. Cumulative link mixed-effects model thresholds are omitted for brevity. An extended version with threshold values is available in Table S16 in Multimedia Appendix 5.

bRandom effects: σ2=9.03; τ00=9.69; participant intraclass correlation coefficient 0.52; marginal R2/conditional R2=0.020/0.527.

cRandom effects: σ2=0.15; τ00=0.03; participant intraclass correlation coefficient 0.19; marginal R2/conditional R2=0.004/0.191.

dRandom effects: σ2=3.29; τ00=2.51; participant intraclass correlation coefficient 0.43; marginal R2/conditional R2=0.015/0.441.

eIRR: incidence rate ratio.

fOR: odds ratio.

gThe predictor was not included in this model.

hMRRI: mean RR interval.

iP values lower than .05 are highlighted in italics.

jLF: low frequency.

kHF: high frequency.

lVLF: very low frequency.

mSDANN: SD of the averages of normal-to-normal intervals.