TABLE 3.
Significant overlapping clusters that associated with hTERT gene methylation and the degree of social functional impairment in PD.
| MNI coordinates |
Cluster voxels | Region | |||
| Methylation | x | y | z | ||
| hTERT ave(b) | –45 | –33 | 45 | 65 | Postcentral_L |
| 49 | Parietal_Inf_L | ||||
| cg6(b1) | –54 | –24 | 30 | 67 | Postcentral_L |
| 46 | Parietal_Inf_L | ||||
| cg6(b2) | –54 | –24 | 39 | 56 | Postcentral_L |
hTERT ave: mean value of hTERT promoter methylation. b1: the significant overlapping clusters that associated with the methylation of cg1295648 and the degree of harm of patients’ social function. b2: the significant overlapping clusters located left postcentral gyrus, that associated with the methylation of cg1295648 and the degree of harm of patients’ social function.