Figure 1. Visit Completion Over 4 Years.

The primary analysis is a time-to-event analysis. Eyes that did not meet the outcome were censored at the last completed visit.

^aIncludes only participants who had at least 1 study eye with a baseline Diabetic Retinopathy Severity Scale score of 35-53.

^bCounts all participants who completed the visit within the following windows (±0.5 y from the target): 183-547 days for 1-year visit, 548-912 days for 2-year visit, 913-1277 days for 3-year visit, and 1278-1642 days for 4-year visit. Numbers of participants who died and were lost to follow-up or those who withdrew are cumulative.

^cIncludes participants who completed only a phone visit after missing the annual visit. Participants completing the visit outside the analysis window were considered as missing the visit: 1 at year 1, 1 at year 2, and 1 at year 3.

^dParticipants completing the visit outside the window were considered as missing the visit.