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. 2022 Aug 5;13:965799. doi: 10.3389/fgene.2022.965799

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Copyright © 2022 Yang, Chen, Wang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune landscape of the NRG-related risk model. (A). Heat map showing the correlation between RiskScore, EstimateScore, the abundance of immune cell infiltration, immune checkpoint expression, and clinical characteristics; (B). From top to bottom: correlation analysis between RiskScore and EstimateScore, immune cell infiltration abundance, and immune checkpoint expression; (C). Box plot showing the differences in the abundances of immune cell infiltrations between the high-risk and low-risk groups; (D). Box plot showing the differences in EsimateScore between the high-risk and low-risk groups; (E). Box plot showing the differences in immune checkpoint expressions between the high-risk and low-risk groups; (F). Correlation between RiskScore and HRD scores; (G). Correlation between RiskScore and MSI scores; (H). Correlation between RiskScore and intratumor heterogeneity scores. *p < 0.05; **p < 0.01; ***p < 0.001.