Table 1:

Ongoing and completed clinical trials involving EVs at www.ClinicalTrials.gov

Clinical Trial	Identifier
Prediction of Immunotherapeutic Effect of Advanced Non-small Cell Lung Cancer	NCT04427475
Clinical Research for the Consistency Analysis of PD-L1 in Cancer Tissue and Plasma Exosome (RadImm01)	NCT02890849
Clinical Research for the Consistency Analysis of PD-L1 in Lung Cancer Tissue and Plasma Exosome Before and After Radiotherapy (RadImm02)	NCT02869685
Anaplastic Thyroid Cancer and Follicular Thyroid Cancer-derived Exosomal Analysis Via Treatment of Lovastatin and Vildagliptin and Pilot Prognostic Study Via Urine Exosomal Biological Markers in Thyroid Cancer Patients	NCT02862470
Study of Molecular Mechanisms Implicated in the Pathogenesis of Melanoma. Role of Exosomes (EXOSOMES)	NCT02310451
Study of Exosomes in Monitoring Patients With Sarcoma (EXOSARC) (EXOSARC)	NCT03800121
Exosomes and Immunotherapy in Non-Hodgkin B-cell Lymphomas (ExoReBLy)	NCT03985696
Hemopurifier Plus Pembrolizumab in Head and Neck Cancer	NCT04453046
Study Investigating the Ability of Plant Exosomes to Deliver Curcumin to Normal and Colon Cancer Tissue	NCT01294072
Pilot Immunotherapy Trial for Recurrent Malignant Gliomas	NCT01550523
Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma	NCT02507583