Table 1.
Reported Dearomatization of Electron-Deficient Phenols to Ortho-Quinones by Various Iodine(V) Reagents: Selected Results5
| |||
|---|---|---|---|
| entry | HVI oxidant | time (h) | yield (%) |
| 1 | Bi(4-CO2Etbipy)HVI | 0.5 | 99 |
| 2 | Bi(4-CO2Etbipy)HVI | 4 | 91 |
| 3 | IBX | 24 | 12 |
| 4 | PhI(O)(OAc)2 | 24 | 0 |
| 5 | PhI(O)(0Tf)2 | 0.66 | 59 |
| 6 | PhI(O)(OTf)2 | 4 | 27 |
| 7 | Bi(4-OMebipy)HVI | 0.66 | 38 |
| 8 | PhI(O)(Py)2(OTf)2 | 0.66 | 0 |