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. 2022 Aug 19;20:124. doi: 10.1186/s12955-022-02032-7

Table 4.

Associations between Frailty and Health-related Quality of Life among older cancer patients: Tobit regression and Logistic regression (N = 229)

EQ-5D-5L utility scores EQ-5D-5L lower quartiles
Variables Estimate SE t P Estimate OR 95%CI P
Sex
Male Ref Ref
Female − 0.003 0.033 − 0.086 0.931 − 0.094 0.910 0.348–2.291 0.844
Marital status
Married Ref Ref
Not married 0.127 0.053 2.376 0.018 − 0.922 0.398 0.056–1.785 0.275
Education level
Uneducated and primary school Ref Ref
Middle school 0.055 0.031 1.761 0.078 − 0.784 0.456 0.173–1.146 0.102
High school and above 0.022 0.036 0.612 0.541 0.110 1.116 0.397–3.110 0.832
Health insurance
UEBMI Ref Ref
URRBMI − 0.029 0.034 − 0.862 0.388 0.159 1.172 0.430–3.244 0.756
Monthly household income, Chinese yuan
 < 1000 Ref Ref
1000–3000 0.020 0.036 0.550 0.582 − 0.723 0.485 0.180–1.284 0.147
3000–5000 − 0.037 0.040 − 0.926 0.354 − 0.232 0.793 0.263–2.371 0.678
5000–10,000 0.002 0.050 0.046 0.963 − 0.855 0.425 0.102–1.682 0.229
Cancer site
Lung Ref Ref
Stomach 0.143 0.035 4.081 0.000 − 1.687 0.185 0.048–0.559 0.006
Esophagus 0.011 0.040 0.268 0.789 − 0.552 0.576 0.182–1.670 0.323
Colorectal 0.167 0.045 3.738 0.000 − 0.827 0.437 0.131–1.318 0.156
Other 0.096 0.041 2.307 0.021 − 1.455 0.233 0.047–0.861 0.044
Cancer stage
I Ref Ref
II − 0.071 0.042 − 1.692 0.091 0.178 1.187 0.275–5.106 0.814
III − 0.150 0.038 − 3.885 0.000 1.369 3.930 1.270–14.158 0.024
IV − 0.131 0.038 − 3.482 0.000 1.250 3.859 1.214–14.239 0.029
Comorbidity
0 Ref Ref
1 0.042 0.029 1.440 0.150 − 0.178 0.837 0.342–1.952 0.687
 ≥ 2 − 0.034 0.042 -0.803 0.422 0.343 1.409 0.438–4.455 0.558
Diagnosis year
 ≤ 1 Ref Ref
 ≥ 2 0.000 0.028 − 0.004 0.997 0.458 1.580 0.735–3.413 0.240
Frailty status
Not Frail Ref Ref
Frail − 0.088 0.031 − 2.861 0.004 1.796 6.024 2.194–19.429 0.001

Abbreviations: UEBMI Urban Employees' Basic Medical Insurance; URRBMI Urban–Rural Residents' Basic Medical Insurance