Table 5.
Co-occurrence of mutations in the analyzed population calculated by the odds ratio method in cBioPortal.
Gene A | Gene B | Neither | A not B | B not A | Both | Log2 odds ratio | p-value | q-value | Tendency | Associations with proteins encoded |
---|---|---|---|---|---|---|---|---|---|---|
DOCK8 | PMS2 | 1,297 | 2 | 1 | 2 | >3 | <0.001 | 0.013 | Co-occurrence | Independent roles |
CR2 | PMS2 | 1,296 | 3 | 1 | 2 | >3 | <0.001 | 0.013 | Co-occurrence | Independent roles |
CR2 | PTEN | 1,278 | 2 | 19 | 3 | >3 | <0.001 | 0.013 | Co-occurrence | Independent roles |
PMS2 | PLCG2 | 1,295 | 1 | 4 | 2 | >3 | <0.001 | 0.013 | Co-occurrence | Independent roles |
CLEC16A | SH3KBP1 | 1,295 | 4 | 1 | 2 | >3 | <0.001 | 0.013 | Co-occurrence | Independent roles |
CR2 | DOCK8 | 1,295 | 3 | 2 | 2 | >3 | <0.001 | 0.014 | Co-occurrence | Independent roles |
DOCK8 | PLCG2 | 1,294 | 2 | 4 | 2 | >3 | <0.001 | 0.017 | Co-occurrence | Shared roles |
MSH5 | PMS2 | 1,291 | 8 | 1 | 2 | >3 | <0.001 | 0.020 | Co-occurrence | Shared roles |
CR2 | PLCG2 | 1,293 | 3 | 4 | 2 | >3 | <0.001 | 0.020 | Co-occurrence | Shared roles |
LRBA | SH3KBP1 | 1,289 | 10 | 1 | 2 | >3 | <0.001 | 0.028 | Co-occurrence | Independent roles |
DOCK8 | MSH5 | 1,290 | 2 | 8 | 2 | >3 | <0.001 | 0.031 | Co-occurrence | Independent roles |
CR2 | MSH5 | 1,289 | 3 | 8 | 2 | >3 | <0.001 | 0.044 | Co-occurrence | Independent roles |
FCGR2A | OR10X1 | 1,301 | 0 | 0 | 1 | >3 | <0.001 | 0.044 | Co-occurrence | Independent roles |
TNFRSF13B | TNFSF13 | 1,301 | 0 | 0 | 1 | >3 | <0.001 | 0.044 | Co-occurrence | Shared roles |
TNFRSF13B | TNFSF12 | 1,301 | 0 | 0 | 1 | >3 | <0.001 | 0.044 | Co-occurrence | Shared roles |
TNFSF13 | TNFSF12 | 1,301 | 0 | 0 | 1 | >3 | <0.001 | 0.044 | Co-occurrence | Shared roles |