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. 2022 Aug 5;13:937872. doi: 10.3389/fimmu.2022.937872

Table 5.

Co-occurrence of mutations in the analyzed population calculated by the odds ratio method in cBioPortal.

Gene A Gene B Neither A not B B not A Both Log2 odds ratio p-value q-value Tendency Associations with proteins encoded
DOCK8 PMS2 1,297 2 1 2 >3 <0.001 0.013 Co-occurrence Independent roles
CR2 PMS2 1,296 3 1 2 >3 <0.001 0.013 Co-occurrence Independent roles
CR2 PTEN 1,278 2 19 3 >3 <0.001 0.013 Co-occurrence Independent roles
PMS2 PLCG2 1,295 1 4 2 >3 <0.001 0.013 Co-occurrence Independent roles
CLEC16A SH3KBP1 1,295 4 1 2 >3 <0.001 0.013 Co-occurrence Independent roles
CR2 DOCK8 1,295 3 2 2 >3 <0.001 0.014 Co-occurrence Independent roles
DOCK8 PLCG2 1,294 2 4 2 >3 <0.001 0.017 Co-occurrence Shared roles
MSH5 PMS2 1,291 8 1 2 >3 <0.001 0.020 Co-occurrence Shared roles
CR2 PLCG2 1,293 3 4 2 >3 <0.001 0.020 Co-occurrence Shared roles
LRBA SH3KBP1 1,289 10 1 2 >3 <0.001 0.028 Co-occurrence Independent roles
DOCK8 MSH5 1,290 2 8 2 >3 <0.001 0.031 Co-occurrence Independent roles
CR2 MSH5 1,289 3 8 2 >3 <0.001 0.044 Co-occurrence Independent roles
FCGR2A OR10X1 1,301 0 0 1 >3 <0.001 0.044 Co-occurrence Independent roles
TNFRSF13B TNFSF13 1,301 0 0 1 >3 <0.001 0.044 Co-occurrence Shared roles
TNFRSF13B TNFSF12 1,301 0 0 1 >3 <0.001 0.044 Co-occurrence Shared roles
TNFSF13 TNFSF12 1,301 0 0 1 >3 <0.001 0.044 Co-occurrence Shared roles