Table 6.
Effect of TXA on rate of transfusion: negative binomial models, inverse probability of treatment weighting applied, controlling for surgeon
| Transfusion timing and type (units) | Rate ratio∗ (95% confidence interval) (TXA compared with EACA) |
|---|---|
| Intraoperative and postoperative | |
| Red blood cells | 0.97 (0.78-1.22) |
| Platelets | 1.23 (0.91-1.69) |
| Fresh frozen plasma | 1.17 (0.73-1.87) |
| Cryoprecipitate | 0.61 (0.26-1.45)∗ |
| Intraoperative | |
| Red blood cells | 1.06 (0.73-1.52) |
| Platelets | 0.79 (0.57-1.09)∗ |
| Fresh frozen plasma | 1.01 (0.56-1.79) |
| Cryoprecipitate | 0.69 (0.13-3.60)∗ |
| Postoperative | |
| Red blood cells | 0.93 (0.74-1.18) |
| Platelets | 1.49 (0.96-2.31) |
| Fresh frozen plasma | 1.25 (0.67-2.35) |
| Cryoprecipitate | 0.58 (0.22-1.54)∗ |
TXA, Tranexamic acid; EACA, Epsilon-aminocaproic acid.
∗
Unable to control for surgeon due to quasi-separation.