Table 5.
Association of postoperative complications with Clavian-Dindo classification (n = 363)
| Variable∗ | Univariate |
Multivariate |
||
|---|---|---|---|---|
| Odds ratio (95% CI) | P value | Odds ratio (95% CI) | P value | |
| Oral management | ||||
| No† | 1 | 1 | ||
| Yes | 0.553 (0.334-0.902) | .019‡ | 0.503 (0.298-0.835) | .009‡ |
| Gender | ||||
| Male† | 1 | – | ||
| Female | 0.753 (0.445-1.249) | .280 | ||
| Age (y) | 1.024 (0.998-1.053) | .080 | ||
| Body mass index | 0.959 (0.894-1.025) | .224 | ||
| ECOG performance status | ||||
| 0† | 1 | – | ||
| 1 | 1.752 (0.830-3.556) | .128 | ||
| %VC | 0.999 (0.991-1.003) | .788 | ||
| %FEV1 | 1.001 (0.995-1.005) | .766 | ||
| Comorbidities | ||||
| Artificial dialysis | 3.103 (0.122-79.033) | .425 | ||
| Interstitial pneumonia | 0.767 (0.039-5.272) | .814 | ||
| Ischemic cardiac disease | 1.300 (0.404-3.618) | .631 | ||
| Cranial nerve disease or cerebrovascular disorder | 1.126 (0.306-3.389) | .843 | ||
| Diabetes mellitus | 1.498 (0.768-2.825) | .221 | ||
| Autoimmune disorder | 6.279 (0.595-136.093) | .136 | ||
| Arrhythmia (medical treatment) | 1.027 (0.224-3.534) | .968 | ||
| Hypertension | 1.343 (0.704-2.475) | .355 | ||
| Smoking status | ||||
| Never smoked† | 1 | – | 1 | – |
| Quit ≥30 d before surgery/exsmoker | 2.235 (1.258-4.150) | .008‡ | 2.153 (1.192-4.057) | .014‡ |
| Quit <30 d before surgery/still smoking | 1.460 (0.547-3.655) | .429 | 1.370 (0.497-3.537) | .526 |
| Preoperative therapy | ||||
| No† | 1 | |||
| Yes | 0 (-,∞) | .982 | ||
| Size of tumor (cm) | 1.070 (0.911, 1.249) | .398 | ||
| Surgical side | ||||
| Right† | 1 | – | ||
| Left | 0.843 (0.498-1.401) | .517 | ||
| Operation time (min) | 1.002 (0.999-1.005) | .134 | ||
| Blood loss (mL) | 1.003 (1.001-1.005) | .011‡ | 1.003 (1.001, 1.005) | .025‡ |
| Surgical approach | ||||
| Thoracotomy† | 1 | – | ||
| VATS | 1.673 (0.431-11.020) | .512 | ||
| Histologic type | ||||
| Adenocarcinoma† | 1 | – | ||
| Nonadenocarcinoma | 1.210 (0.717-2.013) | .468 | ||
| Pathologic staging | ||||
| 0† | 1 | – | ||
| IA and IB | 1.053 (0.252-7.156) | .950 | ||
| IIA and IIB | 2.189 (0.507-15.144) | .342 | ||
| IIIA.and.IIIB | 1.532 (0.343-10.796) | .611 | ||
| IV | 0.308 (0.013-3.722) | .366 | ||
| Albumin (g/dL) | 0.630 (0.370-1.076) | .087 | ||
ECOG, Eastern Cooperative Oncology Group; %VC, vital capacity; %FEV1, forced expiratory volume for 1 second expressed as a percentage of the forced vital capacity; VATS, video-assisted thoracoscopic surgery.
∗
Number of events = 90.
†
Reference category.
‡
P < .05.