Figure E5.

Heart rate (A) and systolic function (B) of mouse hearts 8 weeks after cardio-omentopexy (COP). Control mice were subjected to sham transverse aortic constriction (TAC) surgery for 6 weeks and subsequent sham COP surgery for 8 weeks. COP mice were subjected to sham TAC surgery for 6 weeks and subsequent COP for 8 weeks. TAC mice underwent TAC for 6 weeks and subsequent sham COP surgery for 8 weeks. TAC+COP mice were subjected to TAC for 6 weeks and subsequent COP for 8 weeks. The upper and lower borders of the box represent the upper and lower quartiles. The middle horizontal line represents the median. The upper and lower whiskers represent the maximum and minimum values of nonoutliers. Extra dots represent outliers. P values were determined using 2-way repeated measures analysis of variance followed by post hoc analysis using Mann–Whitney test for comparison between 2 groups. There were no differences in heart rate and ejection fraction between groups (n = 12-13 mice per group).