Figure 1.

Study design. An SCIR injury model was created by aortic arch crossclamping. No immunosuppressants were used, and hBM-MSC or PBS was administered 2 hours after induction. Lower-limb movements were evaluated at each time based on the Basso Mouse Scale. Histologic analysis was performed 8 hours, 24 hours, and 28 weeks later, and real-time RT-PCR was performed 24 hours later. SCIR, Spinal cord ischemia/reperfusion; hBM-MSC, human bone marrow derived mesenchymal stem/stromal cell; PBS, phosphate-buffered saline; RT-PCR, reverse transcription polymerase chain reaction.