Figure 1.

Establishing inactivation of recently terminated rabbits at 121°C for 20 min. A–B, images of the biologic indicator strip from the front (A) and back (B) side. (C) image of the metal autoclave boxes with bedding material-filled autoclave bags. D–E images of the first rabbit carcass with a hole in the skull to place a temperature sensor into the brain (D) and with sensors placed into the interior of the carcass (E). (F) image of the first rabbit carcass fitted into the metal autoclave box. G–H, temperature (°C, left) and pressure (mbar, right) profiles of individual runs with a 3.8 kg (G) and 3.6 kg (H) rabbit carcass. I, zoom-in image of the temperature profile of H (light green box). Gray boxes indicate temperatures ≥ 121°C.