Table 2.
Association between patient characteristics and hazard of death
| Variable | Hazard ratio (95% CI) | P value |
|---|---|---|
| T3 Characteristic treatment∗ | .005 | |
| TSZ | ||
| S + CR | Reference | |
| S | 2.59 (2.09-3.22) | <.0001 |
| CWI | ||
| S + CR | Reference | |
| S | 2.91 (1.89-4.47) | <.0001 |
| ADN | ||
| S + CR | Reference | |
| S | 1.58 (1.17-2.13) | .003 |
| Multiple T3 | ||
| S + CR | Reference | |
| S | 3.36 (2.41-4.69) | <.0001 |
| Age (y) | ||
| <61 | Reference | |
| 61-68 | 1.18 (0.97-1.44) | .09 |
| 68-75 | 1.42 (1.18-1.71) | .0002 |
| >75 | 1.48 (1.22-1.78) | <.0001 |
| Sex | ||
| Male | Reference | |
| Female | 0.73 (0.64-0.83) | <.0001 |
| Charlson-Deyo score | ||
| 0 | Reference | |
| 1 | 1.255 (1.025-1.538) | .0283 |
| 2 | 1.168 (0.857-1.592) | .3248 |
| ≥3 | 1.679 (1.084-2.602) | .0204 |
TSZ, Tumor size >5 and ≤7 cm; S + CR, surgery followed by chemotherapy with or without radiation therapy; S, surgery alone; CWI, chest wall invasion or resection; ADN, additional nodules in the ipsilateral lung, same lobe.
∗
Multivariable Cox regression, with the interaction term of T3 characteristic and treatment type.