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. 2022 Feb 23;10:195–203. doi: 10.1016/j.xjon.2022.02.022

Table 1.

Lipid subcomponent thresholds over the years

Lipid subcomponent 2002 NCEP-ATP III3 2011 ESC4 2016 ESC5 2019 ESC6
LDL-C ≥25% reduction from baseline, and <2.6 mmol/L ≥50% reduction from baseline, and <1.8 mmol/L ≥50% reduction from baseline <1.8 mmol/L ≥50% reduction from baseline <1.4 mmol/L
Percentage of patients with lifetime average levels below recommended LDL-C threshold 81.9% 24.3% 24.3% 5.8%
Non–HDL-C No specific goal No specific goal No specific goal <2.2 mmol/L
TG No specific goal No specific goal No specific goal No specific goal Aim <1.7 mmol/L
TC No specific goal No specific goal No specific goal No specific goal

NCEP-ATP III, National Cholesterol Education Program Adult Treatment Panel III; ESC, European Society of Cardiology; LDL-C, low-density lipoprotein cholesterol; non–HDL-C, non–high-density lipoprotein cholesterol; TG, triglycerides; TC, total cholesterol.