Table 3.
Two-level nested hierarchical Cox proportional hazards regression model of predictors for cardiac death after CABG
| Variable | Cardiac death |
|
|---|---|---|
| Hazards ratio (95% CI) | P value | |
| First layer—significant variables from univariate analysis | ||
| Diabetes mellitus | 3.759 (1.244-11.357) | .019∗ |
| LVEF (>50% vs 30%-50% vs <30%) | 2.325 (1.314-4.116) | .004∗ |
| Left main disease | 0.589 (0.228-1.525) | .276 |
| History of PCI | 1.044 (0.303-3.598) | .946 |
| Second layer—lipid profile subcomponents (calculated separately) | ||
| LDL-C | 2.297 (1.234-4.277) | .009∗ |
| Non–HDL-C | 2.557 (1.461-4.474) | .001∗ |
| HDL-C | 0.343 (0.051-2.322) | .273 |
| TC/HDL-C ratio | 1.740 (1.187-2.552) | .005∗ |
| Triglycerides | 1.686 (1.043-2.725) | .033 |
CI, Confidence interval; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention; LDL-C, low-density lipoprotein cholesterol; non–HDL-C, non–high-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol.
∗
P ≤ .01, statistically significant.