Table E1.
Overall cohort demographics and comorbidities stratified by presence and location of obstructive CAD
| All (N = 793) |
No CAD (N = 321) |
Only anomalous coronary with CAD (N = 142) |
Normal- origin coronary with CAD (N = 330) |
P value | |
|---|---|---|---|---|---|
| Mean ± SD or n (%) |
Mean ± SD or n (%) |
Mean ± SD or n (%) |
Mean ± SD or n (%) |
||
| Demographics | |||||
| Age at CAD imaging, y | 56.6 ± 14.2 | 51.3 ± 16.9 | 59.4 ± 9.95 | 60.7 ± 10.7 | <.0001 |
| Male | 575 (73) | 184 (57) | 120 (85) | 271 (82) | <.0001 |
| Comorbidities | |||||
| Hypertension | 445/789 (56) | 212/319 (66) | 74/141 (52) | 159/329 (48) | <.0001 |
| Tobacco use | 367/780 (47) | 118/320 (37) | 78/139 (56) | 171/321 (53) | <.0001 |
| Arrhythmias | 220/774 (32) | 177/306 (58) | 19/110 (17) | 24/263 (9.1) | <.0001 |
| Heart failure | 152/780 (19) | 81/317 (26) | 25/138 (18) | 46/325 (14) | .0012 |
| Diabetes | 149/774 (19) | 60/320 (19) | 31/137 (23) | 58/317 (18) | .54 |
| Pulmonary disease | 121/776 (16) | 95/318 (30) | 10/137 (7.3) | 16/321 (5) | <.0001 |
| Peripheral artery disease | 69/774 (8.9) | 15/316 (4.8) | 13/137 (9.5) | 41/321 (13) | .0018 |
Baseline characteristics of 793 adult patients diagnosed with AAOCA are shown as counts (and relative frequencies) stratified by the presence and location. Obstructive coronary artery disease (CAD) was defined as >50% stenosis in the left main coronary artery (LMCA) or >70% stenosis in the right coronary artery (RCA), left anterior descending (LAD), or left circumflex (LCx) coronary artery. The frequencies of patients with AAOCA affecting each of the 4 or multiple coronaries were stratified based on the presence and location of any CAD. P value resulted from χ2 tests comparing patients with no CAD, CAD in only the anomalous coronary, and CAD in normal-origin coronaries. SD, Standard deviation; AAOCA, anomalous aortic origin of a coronary artery.