Table E11.

Factors associated with a greater overall coronary artery stenosis within modern subcohort

Factor	Coefficient ± SE	P value	R (%)∗
Coronary-level
Anomalous origin	0.16 ± 0.38	.6	4.3
Intramural	0.45 ± 0.52	.4	15
Interarterial	−0.096 ± 0.52	.8	2
Intraseptal	−0.38 ± 0.75	.6	3
Patient-level
Anomalous coronary: LCx	0.97 ± 0.44	.03	74
Male	1.3 ± 0.36	.0004	99
Older age at assessment†	1.5 ± 0.21	<.0001	100

There was no association between the CAD severity and the presence of an anomalous origin, slit-like orifice, acute angulation, interarterial course, intramural course, intraseptal course, or any of the presumed high-risk courses were combined. Older age, male sex, and AAOCA affecting the anomalous left circumflex were associated with a greater grade of coronary artery stenosis overall. SE, Standard error; LCx, left circumflex; CAD, coronary artery disease; AAOCA, anomalous aortic origin of a coronary artery.

^∗Bagging reliability represents the proportion of 1000 bootstrap logistic regression models, with the assumption of independence, in which the variable was retained with P < .05.

^†Exp [Age/50], exponential transformation.