Table E5.
Modern subcohort demographics and coronary anatomic features stratified by anomalous coronary
| Anomalous coronary |
P value | |||||
|---|---|---|---|---|---|---|
| LMCA |
LAD |
LCx |
RCA |
Multiple |
||
| Mean ± SD or 15/50/85 percentile or n (%) |
Mean ± SD or 15/50/85 percentile or n (%) |
Mean ± SD or 15/50/85 percentile or n (%) |
Mean ± SD or 15/50/85 percentile or n (%) |
Mean ± SD or 15/50/85 percentile or n (%) |
||
| Demographics | ||||||
| Age | 51.3 ± 16.6 | 54.6 ± 13.6 | 61.7 ± 15.8 | 50.7 ± 17.8 | 58.2 ± 5.52 | .0025 |
| Interval, AAOCA diagnosis to CAD imaging | 0/0.11/3.79 | 0/0.07/3.91 | 0/0/1.53 | 0/0/0.57 | 0/0/0.05 | |
| Male | 31/53 (58) | 3/7 (43) | 27/47 (57) | 93/162 (57) | 1/4 (25) | .68 |
| Comorbidities | ||||||
| Congestive heart failure | 19/53 (36) | 2/7 (29) | 13/47 (28) | 34/162 (21) | 0/4 (0) | .18 |
| Arrhythmias | 30/53 (57) | 5/7 (71) | 31/47 (66) | 97/162 (60) | 2/4 (50) | .83 |
| Pulmonary disease | 20/53 (38) | 3/7 (43) | 11/47 (23) | 46/162 (28) | 1/4 (25) | .51 |
| Diabetes | 10/53 (19) | 0/7 (0) | 16/47 (34) | 32/162 (20) | 0/4 (0) | .093 |
| Peripheral artery disease | 3/53 (5.7) | 0/7 (0) | 1/47 (2.1) | 7/162 (4.3) | 0/4 (0) | .86 |
| Hypertension | 36/53 (68) | 5/7 (71) | 36/47 (77) | 114/162 (70) | 4/4 (100) | .62 |
| Tobacco use | 17/53 (32) | 0/7 (0) | 16/47 (34) | 54/162 (33) | 2/4 (50) | .4 |
| Arise from | <.0001 | |||||
| Opposite sinus | 40/53 (75) | 5/7 (71) | 28/47 (60) | 126/162 (78) | 2/4 (50) | |
| Noncoronary sinus | 0/53 (0) | 0/7 (0) | 0/47 (0) | 1/162 (0.62) | 0/4 (0) | |
| Opposite artery | 11/53 (21) | 2/7 (29) | 19/47 (40) | 4/162 (2.5) | 0/4 (0) | |
| Suprasinus | 2/53 (3.8) | 0/7 (0) | 0/47 (0) | 31/162 (19) | 2/4 (50) | |
| Morphology and course | ||||||
| Slit-like Orifice | 8/42 (19) | 0/4 (0) | 1/15 (6.7) | 79/126 (63) | 0/3 (0) | <.0001 |
| Acute angulation | 11/45 (24) | 0/4 (0) | 3/17 (18) | 64/109 (59) | 1/3 (33) | <.0001 |
| Greater-risk course (any of 3 to follow) | 37/52 (71) | 5/5 (100) | 1/33 (3) | 133/152 (88) | 3/4 (75) | <.0001 |
| Intramural course | 11/47 (23) | 0/3 (0) | 0/22 (0) | 91/135 (67) | 0/4 (0) | <.0001 |
| Interarterial course | 27/50 (54) | 3/3 (100) | 0/32 (0) | 118/145 (81) | 2/3 (67) | <.0001 |
| Intraconal or intraseptal course | 25/47 (53) | 4/5 (80) | 1/24 (4.2) | 2/117 (1.7) | 1/3 (33) | <.0001 |
| Dominance | ||||||
| Left | 1/50 (2) | 1/7 (14) | 4/44 (9.1) | 16/151 (11) | 0/4 (0) | |
| Right | 49/50 (98) | 6/7 (86) | 39/44 (89) | 120/151 (79) | 4/4 (100) | .088 |
| Codominant | 0/50 (0) | 0/7 (0) | 1/44 (2.3) | 15/151 (9.9) | 0/4 (0) | |
LMCA, Left main coronary artery; LAD, left anterior descending coronary artery; LCx, left circumflex; RCA, right coronary artery; SD, standard deviation; AAOCA, anomalous aortic origin of a coronary artery; CAD, coronary artery disease.