Figure 5:

CPS-specific antibodies between colonized (C) and non-colonized (NC) individuals in serum and nasal and vaginal mucosa. An individual was defined as colonized with a serotype if they carried this serotype at one or more visits. Concentrations plotted are, for each individual, the average concentrations between all visits. Medians compared with a Mann-Whitney test in serum (A), vaginal (B), and nasal samples (C), concentration on log scale. Fold change in serum (D), vaginal (E), and nasal samples (F) was calculated between levels measured in the last collected sample over the first collected sample for each individual. Concentrations of serum CPS-specific IgG in µg/ml, of vaginal CPS-specific IgG/total IgG in ‰ and of nasal CPS-specific IgA/total IgA in AU.