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. 2022 Jun 1;209(2):225–235. doi: 10.1093/cei/uxac055

Figure 2:

Figure 2:

The levels of serum IL-6 and its receptors are similar in patients with SIRS or sepsis. (A) Serum concentration of IL-6 in healthy volunteers (n = 8), patients with SIRS (n = 7) and patients with sepsis (n = 12). (B) Mean fluorescence intensity (MFI) of the IL-6 membrane receptor (mIL-6R) on peripheral blood monocytes (FSCmed SSCmed CD45+ CD14+) of healthy volunteers (n = 9), patients with SIRS (n = 7) and patients with sepsis (n = 11). (C) Serum concentration of the soluble IL-6 receptor (sIL-6R) in healthy volunteers (n = 5), patients with SIRS (n = 8) and patients with sepsis (n = 11). (D) Serum concentration of the soluble gp130 receptor (sgp130) in healthy volunteers (n = 7), patients with SIRS (n = 16) and patients with sepsis (n = 16). Graphs represent individual data (each symbol represents data from one individual), mean and standard error of the mean. ns, not significant, **P < 0.01, ***P < 0.001, Kruskal–Wallis test with Dunn’s multiple comparisons test.