Table 4.
ORs (and 95% CIs) of cognitive impairment and severe CSVD burden score according to tertiles of TyG index levels.
| TyG index levels, median (range) | ||||
|---|---|---|---|---|
| Quartile 18.39 (≤8.71) | Quartile 28.96 (8.72-9.21) | Quartile 39.58 (≥9.22) | P value for trend 1 | |
| Cognitive impairment | ||||
| Model 1 Model 2 Model 3 |
1.00 (reference) 1.00 (reference) 1.00 (reference) |
1.771 (1.007-3.114) 1.809 (1.002-3.264) 1.748 (0.926-3.299) |
4.059 (2.269-7.260) 4.709 (2.515-8.817) 3.298 (1.685-6.452) |
< 0.001 < 0.001 < 0.001 |
| Severe CSVD burden score | ||||
| Model 1 Model 2 Model 3 |
1.00 (reference) 1.00 (reference) 1.00 (reference) |
1.040 (0.600-1.803) 1.066 (0.603-1.885) 1.082 (0.589-1.986) |
1.998 (1.145-3.485) 2.341 (1.294-4.328) 1.933 (1.010-3.698) |
0.014 0.005 0.047 |
1Tests for trend were conducted by treating the tertiles as a continuous variable and assigning the median for each quintile.
Model 1: Unadjusted; Model 2: Adjusted for age, sex and education. Model 3: Adjusted for age, sex, education, hypertension, history of stroke, SBP, HbA1c, HDL, insulin or metformin usage and serum tHcy.