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. 2022 Aug 5;13:916200. doi: 10.3389/fimmu.2022.916200

Table 2.

Factors available to assess the efficacy of HLA antibody desensitization.

Pre-Transplant Post-Transplant
  • Change in HLA antibodies

    • Solid-phase assay: antibody MFI, change in reactivity pattern, C1q status, titer

  • • Flow cytometric crossmatch: B and T cell positive or negative

  • Engraftment

  • • Days until chimerism (CD3+ and CD33+)

  • Disease relapse

  • Graft Versus Host Disease

  • • Acute or chronic

  • Clinical outcome

  • • Non-relapse mortality

  • • Opportunistic infection

  • • Survival (overall and progression-free)