Fig. 1. Modeling workflow.

The figure shows the modeling procedure and methods implemented in the study. Orange dots represent a known virus in the observed ($G_c$) and predicted networks ($G_{predicted}$), blue dots represent novel viruses in the predicted network ($G_{predicted}$). Virus-host networks: $G_c$, represents a unipartite observed network of known zoonotic and non-zoonotic viruses with nodes representing viruses and edges representing shared hosts. $G_{predicted}$represents the predicted unipartite network generated after predicting possible linkages between 531 novel viruses (blue) and known viruses. The node size is proportional to the betweenness centrality.