Adipocyte mTORC1 deficiency reduces iWAT BCAA oxidation and blocks the upregulation in this process induced by rosiglitazone. Serum branched-chain amino acids (BCAA) (A) and inguinal white adipose tissue (iWAT) valine oxidation (B), and mRNA levels of SLC25A44 (C), BCAT2 (D), BCKDHA (E), BCKDHB (F), DBT (G), DLD (H) and BCKDK (I) in RapWT and RapKO mice fed with high-fat diet (HFD) containing or not rosiglitazone (RSG, 30 mg/kg/day) for 8 weeks. Values are expressed as mean ± SEM. n= 5–10 mice per group. Means not sharing a common superscript are significantly different from each other, p ≤ 0.05.