Table 1. Major phospholipid (PL)-binding proteins.

Protein	Size	Location	Description
Annexins	36 kd, 70 aa, repeats in α − helix	II: cell granules, membranes, rafts V: placenta	Ca 2+ -dependent PL binding; II binds S100A10, t-PA
β 2 -Glycoprotein I	48 kd, 326 aa	Plasma: 200 µg/mL	Multimer; circular form assumes J-shape when bound to PL
Cardiolipin	1,466 g/mol	Mitochondrial inner membrane	Diphosphatidyl glycerol; structural integrity of respiratory chain
Vimentin	310 aa-polymerizes	Skin and other organs; cell surface and extracellular matrix	Phosphorylated filamentous protein

Abbreviations: aa, amino acids; t-PA, tissue plasminogen activator.