Table 4.

The antidiarrheal effect of different extracts of B. lacera leaves on castor oil-induced test in mice.

Doses (ml/kg, b.w; p.o)	Onset of diarrhea	Average number of wet feces	Average number of total feces	Average weight of wet feces (g)	Average weight of total feces (g)
CTL 10	76.2 ± 2.21	10.30 ± 3.21	14.2 ± 2.32	0.42 ± 0.12	0.54 ± 0.28
Loperamide 2	203.6 ± 4.71∗∗∗	2.67 ± 2.31∗∗∗	3.12 ± 2.34∗∗∗	0.08 ± 0.23∗∗∗	0.12 ± 0.87∗∗∗
BLE 200	86.9 ± 2.42∗	4.33 ± 2.12∗∗∗	5.36 ± 1.32∗∗∗	0.22 ± 0.32∗∗∗	0.28 ± 0.65∗∗∗
BLE 400	107.3 ± 1.85∗∗∗	3.67 ± 1.39∗∗∗	6.23 ± 2.14∗∗∗	0.18 ± 0.85∗∗∗	0.33 ± 0.85∗∗∗
BLP 200	89.38 ± 3.28∗	4.67 ± 2.54∗∗∗	5.38 ± 3.21∗∗∗	0.28 ± 0.12∗∗∗	0.31 ± 0.60∗∗∗
BLP 400	110.57 ± 1.32∗∗∗	4.00 ± 2.36∗∗∗	6.56 ± 1.65∗∗∗	0.22 ± 0.45∗∗∗	0.28 ± 0.48∗∗∗
BLC 200	96.23 ± 3.21∗∗	6.00 ± 3.12∗∗	8.39 ± 2.31∗∗	0.26 ± 0.18∗∗∗	0.39 ± 0.28∗∗∗
BLC 400	84.85 ± 2.31∗	5.67 ± 2.14∗∗∗	8.32 ± 3.24∗∗	0.24 ± 0.38∗∗∗	0.32 ± 0.83∗∗∗
BLA 200	90.43 ± 1.38∗∗	7.33 ± 2.14∗	11.23 ± 1.78∗∗	0.37 ± 0.88∗	0.52 ± 0.62
BLA 400	89.32 ± 2.31∗∗	7.00 ± 2.68∗	9.27 ± 1.88∗∗	0.32 ± 0.56∗	0.48 ± 0.38

Values are expressed as mean ± SEM (n = 5). CTL: negative control (1% tween 80 in water), STD: positive control (loperamide at 5 mg/kg body weight). ^∗∗∗p < 0.001, ^∗∗p < 0.01, ^∗p < 0.05 compared to control compared to negative control).