Fig. 4.
Demonstration of wound healing model using moMSCORS. moMSCORS (n=17) were applied on the induced full-thickness wound on the one side of the bilateral dorsum skin of C57BL/6 mice (n=27). Young healthy C57BL/6 mice (3 months) were chosen for this study. Using punch biopsy with the diameter of 5 mm, artificial wound was induced by punching through both layers of the dorsal skin. 106 moMSCORS were resuspended with 50 uL PBS, and carefully applied onto the wound. PBS without cells was used in the untreated group. The mice were kept, and wound size was documented using camera on the day 1, 3, 5, 7, 9, 11, 14 after the cell seeding with a ruler aside for scaling