Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 26;18(6):2059–2073. doi: 10.1007/s12015-022-10378-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Exosomes were successfully isolated from ADMSCs medium; ADMSC-Exos promotes wound healing. A Exosomes were observed by transmission electron microscopy (TEM). B The expression of the exosome protein markers CD9 and CD63 was confirmed by Western blotting. C Nanoparticle tracking analysis (NTA) showed that the ADMSC-Exos distribution diameter ranged from 40 to 100 nm. D, E As can be seen from the wound images at different time points, the wound shrinkage rate of the AMDMSC-Exos group was significantly faster than that of the PBS group and the blank control group. At the 14th day, the remaining wound area was significantly reduced compared with the other two groups. F Traces of wound-bed closure during 14 days in vivo for each treatment category. The data were statistically analyzed using GraphPad. Results are presented as mean ± SD; n = 3; ^*p < 0.05, compared with PBS and blank control group