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. 2022 Feb 21;18(6):2164–2178. doi: 10.1007/s12015-022-10350-y

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Transcriptome analysis of miR151 or miR5100 transfected mouse BMSCs. (A) The statistically significant changes in gene expression in miR151 or miR5100 transfected mouse BMSCs compared to control, non-transfected cells. Red – up-regulated transcripts; green - down-regulated transcripts; grey – sum of up-regulated and down-regulated transcripts. (B) Venn diagram of differentially expressed genes in miR151 or miR5100 transfected mouse BMSCs compared to non-transfected control cells. (C) Volcano plot of fold changes in gene expression in miR151 or miR5100 transfected mouse BMSCs compared to non-transfected controls. (D) STRING analysis of ABLIM1, ADAMTS5, MMP12, and SDF-1 (CXCL12) interactions. The transcripts characterized by statistically significant difference in expression (microarray analysis) have been highlighted - red. (E) STRING analysis of IGFBP2 interactions. The transcripts characterized by statistically significant difference in expression (microarray analysis) have been highlighted - red.