Table 3:
Statistics for cognitive performance at last visit by pathologic feature and their interaction with group
PART vs ADNC | Braak I-II vs Braak III-IV | LATE-NC− vs LATE-NC + | Vasc− vs Vasc+ | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Coefficient (95% CI) | Group P value | Coefficient (95% CI) | Braak P value | Group Interaction P value | Coefficient (95% CI) | LATE P value | Group Interaction P value | Coefficient (95% CI) | Vasc P value | Group Interaction P value | |
MMSE | −0.67 (−3.25 – 1.91) | 0.606 | −4.38 (−7.01 – −1.75) | 0.001 | 0.115 | −5.8 (−8.62 – −2.98) | <0.001 | 0.769 | −1.20 (−4.08 – 1.67) | 0.408 | 0.053 |
DRS | −1.33 (−10.56 – 7.91) | 0.776 | −10.81 (−20.53 – −1.08) | 0.03 | 0.256 | −17.51 (−27.89 – −7.14) | 0.001 | 0.614 | −10.20 (−20.32 – −0.08) | 0.048 | 0.118 |
CDR-sob | 1.12 (−1.50 – 3.75) | 0.396 | 6.88 (4.62 – 9.13) | <0.001 | 0.966 | 5.17 (2.10 – 8.24) | 0.001 | 0.737 | 1.32 (−1.59 – 4.23) | 0.369 | 0.133 |
Memory | −0.02 (−0.68 – 0.64) | 0.956 | −0.90 (−1.60 – −0.21) | 0.011 | 0.173 | −0.82 (−1.59 – −0.05) | 0.037 | 0.858 | −0.13 (−0.89 – 0.63) | 0.741 | 0.749 |
Executive | 0.05 (−0.83 – 0.94) | 0.904 | −0.03 (−0.97 – 0.92) | 0.958 | 0.791 | 0.28 (−0.76 – 1.32) | 0.596 | 0.445 | −1.30 (−2.27 – −0.34) | 0.009 | 0.117 |
Visuospatial | −0.34 (−1.30 – 0.62) | 0.487 | −0.27 (−1.31 – 0.76) | 0.600 | 0.655 | −0.89 (−2.02 – 0.24) | 0.12 | 0.65 | −0.90 (−1.98 – 0.18) | 0.102 | 0.430 |
Language | −0.50 (−1.28 – 0.28) | 0.205 | −0.62 (−1.46 – 0.22) | 0.145 | 0.057 | −1.08 (−2.00 – −0.16) | 0.021 | 0.627 | 0.39 (−0.51 – 1.29) | 0.391 | 0.153 |
For each cognitive test or composite, the coefficient (99% Confidence Interval) for the cross-sectional performance at the last visit is provided along with the p value for each pathologic term as indicated along the top. For each pathologic term other than the Group term (i.e., PART vs ADNC), the p value for the interaction of the pathologic term with Group is also provided so assess if the effects differ between those with PART or ADNC.