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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Ann Neurol. 2022 Jul 11;92(3):425–438. doi: 10.1002/ana.26438

Table 3:

Statistics for cognitive performance at last visit by pathologic feature and their interaction with group

PART vs ADNC Braak I-II vs Braak III-IV LATE-NC− vs LATE-NC + Vasc− vs Vasc+
Coefficient (95% CI) Group P value Coefficient (95% CI) Braak P value Group Interaction P value Coefficient (95% CI) LATE P value Group Interaction P value Coefficient (95% CI) Vasc P value Group Interaction P value
MMSE −0.67 (−3.25 – 1.91) 0.606 −4.38 (−7.01 – −1.75) 0.001 0.115 −5.8 (−8.62 – −2.98) <0.001 0.769 −1.20 (−4.08 – 1.67) 0.408 0.053
DRS −1.33 (−10.56 – 7.91) 0.776 10.81 (−20.53 – −1.08) 0.03 0.256 17.51 (−27.89 – −7.14) 0.001 0.614 10.20 (−20.32 – −0.08) 0.048 0.118
CDR-sob 1.12 (−1.50 – 3.75) 0.396 6.88 (4.62 – 9.13) <0.001 0.966 5.17 (2.10 – 8.24) 0.001 0.737 1.32 (−1.59 – 4.23) 0.369 0.133
Memory −0.02 (−0.68 – 0.64) 0.956 0.90 (−1.60 – −0.21) 0.011 0.173 0.82 (−1.59 – −0.05) 0.037 0.858 −0.13 (−0.89 – 0.63) 0.741 0.749
Executive 0.05 (−0.83 – 0.94) 0.904 −0.03 (−0.97 – 0.92) 0.958 0.791 0.28 (−0.76 – 1.32) 0.596 0.445 1.30 (−2.27 – −0.34) 0.009 0.117
Visuospatial −0.34 (−1.30 – 0.62) 0.487 −0.27 (−1.31 – 0.76) 0.600 0.655 −0.89 (−2.02 – 0.24) 0.12 0.65 −0.90 (−1.98 – 0.18) 0.102 0.430
Language −0.50 (−1.28 – 0.28) 0.205 −0.62 (−1.46 – 0.22) 0.145 0.057 1.08 (−2.00 – −0.16) 0.021 0.627 0.39 (−0.51 – 1.29) 0.391 0.153

For each cognitive test or composite, the coefficient (99% Confidence Interval) for the cross-sectional performance at the last visit is provided along with the p value for each pathologic term as indicated along the top. For each pathologic term other than the Group term (i.e., PART vs ADNC), the p value for the interaction of the pathologic term with Group is also provided so assess if the effects differ between those with PART or ADNC.