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. Author manuscript; available in PMC: 2023 Aug 17.
Published in final edited form as: Neuron. 2022 Aug 10;110(16):2646–2663.e6. doi: 10.1016/j.neuron.2022.06.022

Figure 4. Anxa2 is the most potent of the 6 regeneration-associated genes that promote significant axon regeneration after ONC injury.

Figure 4.

(A) Confocal images of optic nerve wholemounts after optical clearance showing maximum intensity projection of regenerating fibers labeled with CTB-Alexa 555 at 14dpc. Scale bar, 100 μm. *: crush site. (B) Quantification of regenerating fibers at different distances distal to the lesion site. Data are presented as means ± s.e.m, n = 8 in all groups except the Acaa2 group (n = 10). *: p<0.05, **: p<0.01, ***: p<0.001, ****: p<0.0001, two-way ANOVA with Sidak’s multiple comparisons test.

See also Figure S5