Table 5.

Severity of BPSD and perceived stress, depression, and burden reported by caregivers (multivariable linear regression analysis).

	PSS		PHQ-9		ZBI-22
	Coefficient* (SE)	p-value	Coefficient* (SE)	p-value	Coefficient* (SE)	p-value
Delusion	0.133 (0.742)	0.858	0.010 (0.449)	0.981	− 0.652 (1.573)	0.679
Hallucinations	0.179 (0.959)	0.853	− 0.163 (0.581)	0.780	0.769 (2.033)	0.706
Agitation	1.350 (0.823)	0.105	1.173 (0.499)	0.021	4.792 (1.738)	0.007
Dysphoria	− 0.725 (0.840)	0.391	0.728 (0.509)	0.157	1.645 (1.770)	0.356
Anxiety	0.259 (0.676)	0.703	− 0.329 (0.409)	0.424	− 0.758 (1.429)	0.597
Euphoria	− 1.339 (0.912)	0.884	− 0.350 (0.552)	0.528	0.427 (1.923)	0.825
Apathy	0.500 (0.669)	0.457	− 0.096 (0.405)	0.814	0.067 (1.415)	0.962
Disinhibition	0.799 (0.754)	0.293	− 0.129 (0.457)	0.778	2.115 (1.614)	0.194
Irritability	1.068 (0.724)	0.144	0.253 (0.439)	0.565	1.285 (1.540)	0.407
Aberrant motor behavior	− 0.726 (0.563)	0.201	− 0.317 (0.341)	0.355	− 1.280 (1.191)	0.286
Sleep disorders	1.009 (0.629)	0.112	0.735 (0.381)	0.049	1.805 (1.362)	0.189
Appetite/eating behavior	− 0.212 (0.591)	0.721	0.093 (0.358)	0.795	− 0.849 (1.283)	0.510

AD Alzheimer’s disease, BPSD behavioral and psychological symptoms of dementia, PSS perceived stress scale, PHQ-9 patient health questionnaire-9, SE standard error, ZBI-22 22-item Zarit Burden Interview. Adjusted for caregiver age, sex, severity of AD, and other domains of BPSD.

Bold values indicate statistical significance (p ≤ 0.05).

*Unstandardized coefficients.