Table 1.
Patient-derived fibrolamellar hepatocellular carcinoma organoids
| Patient # | ID | -Sex | Normal/primary/metastasis | Previous treatment |
|---|---|---|---|---|
| FLC6 | M1 | F | M-ant. Inf. Pericardial LN | Naive |
| M2 | M-ant. Sup. Pericardial LN | Naive | ||
| FLC7 | N | M | N-liver | Naive |
| P | P-liver | Naive | ||
| M1 | M-r periportal lymph node | Naive | ||
| M2 | M-l periportal lymph node | Naive | ||
| FLC8 | M | F | M-abdominal wall | Experienced |
| FLC9 | N | M | N-liver | Experienced |
| M1 | M-ascites | Experienced | ||
| M2 | M-omental nodule | Experienced | ||
| FLC11 | N | M | N-liver | Experienced |
| M1 | M-lymph node | Experienced | ||
| FLC12 | N | M | N-liver | Experienced |
| M1 | M-liver | Experienced | ||
| M2 | M-lymph node | Experienced | ||
| M3 | M-retroperitoneal lymph node | Experienced | ||
| FLC13 | N | F | N-liver | Experienced |
| P | P-liver | Experienced | ||
| FLC14 | N | M | N-liver | Experienced |
| P | P-liver | Experienced | ||
| FLC15 | M1 | F | M-lung nodule | Experienced |
Twenty-one patient-derived organoid lines cultured from nine patients with fibrolamellar hepatocellular carcinoma including six non-tumor liver (“normal” or N) organoid lines, three primary liver tumor (P) organoid lines, and 12 metastatic (M, M1–3) organoid lines. Patient sex, tumor location, and treatment prior to tumor resection are listed. Experienced, at least one chemotherapeutic agent; naïve, no treatment prior to resection.