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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Acta Biomater. 2022 Feb 20;163:312–325. doi: 10.1016/j.actbio.2022.02.023

Table 2.

Deformation of the AL due to treatment with buffer or TrypLE (n = 8 per group). Fig. 4. shows representative results from DVC. Radial and circumferential expansion defined by Err and Eθθ , respectively, calculated from DVC of image volumes taken at 10 mmHg before and after treatment. Expansion was averaged in the whole specimen, or regionally in the central and in the combined peripheral and rim regions (Peri + Rim). The radial expansion was negative (i.e., contraction) and significantly smaller (i.e., more contraction) due to TrypLE than buffer (p ≤ 0.007). P-values are from Mann-Whitney U tests comparing the buffer and TrypLE groups, p<0.05 is significant. Values are mean ± std.

Region Group Expansion p-value
Radial Expansion Whole Buffer 0.005 ± 0.007 0.004
TrypLE −0.029 ± 0.027
Central Buffer 0.010 ± 0.014 0.44
TrypLE 0.001 ± 0.021
Peri + Rim Buffer 0.002 ± 0.016 0.007
TrypLE −0.044 ± 0.038
Circumferential Expansion Whole Buffer 0.014 ± 0.013 0.3
TrypLE 0.006 ± 0.017
Central Buffer 0.016 ± 0.017 0.38
TrypLE 0.012 ± 0.010
Peri + Rim Buffer 0.012 ± 0.011 0.51
TrypLE 0.002 ± 0.023