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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Acta Biomater. 2022 Feb 20;163:312–325. doi: 10.1016/j.actbio.2022.02.023

Table 5.

Strain response of the AL due to IOP increase from 10 to 30 mmHg, before and after treatment. Fig. 8. shows representative results from DVC. Three normal strain components (Err , Exx , Eyy ) and Emax were significantly greater after treatment with TrypLE than before (n = 8, p ≤ 0.04). Values are mean ± std, and p-values are from Wilcoxon signed rank test comparing the values before vs. after treatment within one treatment group (n = 8 per group).

Group Before After p-value Before vs. After
Err Buffer 0.010 ± 0.005 0.014 ± 0.004 0.08
TrypLE 0.006 ± 0.008 0.028 ± 0.009 0.01
Eθθ Buffer 0.028 ± 0.014 0.026 ± 0.009 0.38
TrypLE 0.027 ± 0.009 0.033 ± 0.010 0.36
E Buffer 0.000 ± 0.001 0.001 ± 0.001 0.38
TrypLE 0.000 ± 0.002 0.000 ± 0.002 0.92
Exx Buffer 0.028 ± 0.011 0.027 ± 0.010 0.64
TrypLE 0.023 ± 0.007 0.032 ± 0.007 0.04
Eyy Buffer 0.011 ± 0.007 0.012 ± 0.006 0.11
TrypLE 0.011 ± 0.007 0.029 ± 0.010 0.01
Exy Buffer 0.002 ± 0.009 0.003 ± 0.008 0.74
TrypLE 0.004 ± 0.006 0.006 ± 0.008 0.55
Emax Buffer 0.042 ± 0.018 0.040 ± 0.012 0.48
TrypLE 0.038 ± 0.009 0.051 ± 0.012 0.04
Emin Buffer −0.003 ± 0.006 0.000 ± 0.005 0.20
TrypLE −0.004 ± 0.008 0.010 ± 0.007 0.01
γmax Buffer 0.023 ± 0.011 0.020 ± 0.006 0.46
TrypLE 0.021 ± 0.006 0.020 ± 0.005 0.46
Ezz Buffer 0.000 ± 0.003 0.000 ± 0.002 0.98
TrypLE 0.001 ± 0.007 −0.002 ± 0.005 0.31