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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Acta Biomater. 2022 Feb 20;163:312–325. doi: 10.1016/j.actbio.2022.02.023

Table 6.

Strain response of the PPS due to IOP increase from 10 to 30 mmHg, before and after treatment. The principal strains (Emax, Emin, γmax ) and Eθθ were significantly greater after treatment with TrypLE than before (n = 8, p ≤ 0.02). Values are mean ± std, and p-values are from Wilcoxon signed rank test comparing the values before vs. after treatment within one treatment group (n = 8 per group).

Group Before After p-value Before vs. After
Err Buffer 0.0001 ± 0.0035 −0.0006 ± 0.0041 0.38
TrypLE 0.0003 ± 0.0064 −0.0009 ± 0.0056 0.20
Eθθ Buffer 0.0037 ± 0.0014 0.0047 ± 0.0036 0.72
TrypLE 0.0049 ± 0.0039 0.0068 ± 0.0053 0.02
E Buffer 0.0008 ± 0.0035 0.0009 ± 0.0019 0.46
TrypLE 0.0005 ± 0.0018 0.0006 ± 0.0012 0.30
Exx Buffer 0.0003 ± 0.0020 −0.0002 ± 0.0034 0.53
TrypLE −0.0008 ± 0.0058 −0.0008 ± 0.0034 0.95
Eyy Buffer 0.0034 ± 0.0020 0.0043 ± 0.0037 0.71
TrypLE 0.0060 ± 0.0033 0.0067 ± 0.0028 0.40
Exy Buffer −0.0009 ± 0.0020 0.0001 ± 0.0025 0.64
TrypLE −0.0011 ± 0.0011 −0.0011 ± 0.0020 0.97
Emax Buffer 0.0141 ± 0.0092 0.0145 ± 0.0071 0.84
TrypLE 0.0149 ± 0.0073 0.0192 ± 0.0107 0.02
Emin Buffer −0.0103 ± 0.0092 −0.0104 ± 0.0028 0.20
TrypLE −0.0096 ± 0.0090 −0.0133 ± 0.0094 0.04
γmax Buffer 0.0122 ± 0.0091 0.0124± 0.0046 1.00
TrypLE 0.0123 ± 0.0079 0.0162 ± 0.0098 0.01