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. 2022 Jul 20;14(7):e27085. doi: 10.7759/cureus.27085

Table 2. Summary of case reports on acetone toxicity available in literature.

Case Study Reference        Route  of exposure Presenting Symptoms and findings      
Renshaw et al, 1956 [16] Absorption from lightweight cast    Unconsciousness, vomiting, hematemesis   
Hift et al, 1961 [17]      Absorption from synthetic plaster case   Drowsiness, irritability, abdominal pain, coffee-ground emesis, acetone breath   
Gitelson et al, 1966 [13] Ingestion   Coma    
Savage et al, 2007 [18] Ingestion (9-month-old baby sucking on nail polish remover pads)   Coma  
Kumarvel et al. 2007 [19]   Ingestion   Respiratory distress, tachycardia, hypertension, tachypnea, fruity odor on breath   
Piatkowski et al, 2007 [20] Inhalation   Skin burns from acetone, corneal erosion, bronchial injury  
Kallenberg et al. 2008 [21 Possible ingestion   Lethargic state with markedly increased muscle tone in the upper extremities. MRI brain showed vasogenic edema    
Umeh et al, 2021  [15] Ingestion   Cardiac arrest/asystole, hypotension, altered mental status, ulcerated and necrotic esophagus and stomach on endoscopy, ultimately death