TABLE 3.
Univariate analysis of the association between clinical factors and venous thromboembolic recurrence in patients with cancer and catheter‐related thrombosis
| Variable | VTE recurrence | |||
|---|---|---|---|---|
| 3 months | 6 months | |||
| OR (95% CI) | p | OR (95% CI) | p | |
| Age, years | 0.99 (0.96–1.02) | 0.57 | 1.00 (0.97–1.03) | 0.99 |
| Sex | ||||
| Female | Reference | |||
| Male | 2.22 (0.81‐7.09) | 0.14 | 1.96 (0.80–5.26) | 0.15 |
| Weight, kg | 0.98 (0.95–1.00) | 0.09 | 0.99 (0.96–1.01) | 0.20 |
| Cancer type | ||||
| Hematologic | Reference | |||
| Solid | 0.42 (0.13–1.16) | 0.11 | 0.48 (0.18–1.16) | 0.12 |
| Concurrent PE | 0.82 (0.04–4.41) | 0.85 | 1.39 (0.21–5.39) | 0.68 |
| Prior history of VTE | ||||
| No | Reference | |||
| Yes | 0.68 (0.11–2.54) | 0.62 | 1.20 (0.33–3.42) | 0.76 |
| Timing of catheter removal | ||||
| Anticoagulants started before catheter removed | Reference | |||
| Catheter was not removed | 0.66 (0.03–5.30) | 0.72 | 0.32 (0.02–1.94) | 0.30 |
| Catheter removed before anticoagulants started | 5.13 (1.61–22.79) | 0.01 | 2.91 (1.14–8.41) | 0.03 |
| Anticoagulants prescribed | ||||
| No | Reference | |||
| Yes | 0.64 (0.23–2.06) | 0.41 | 0.54 (0.22–1.49) | 0.21 |
| Catheter reinserted after removal | ||||
| No | Reference | |||
| Yes | 7.28 (2.01–46.70) | 0.009 | 4.09 (1.47–14.48) | 0.01 |
Note: Age and weight are continuous variables with odds ratio associated with a one‐unit increment (per each 1‐year or 1‐kg increase, respectively) for each variable. Boldface indicates statistical significance.
Abbreviations: CI, confidence interval; OR, odds ratio; PE, pulmonary embolism; VTE, venous thromboembolism.