Figure 9.

Upstream regulator analysis in oocyte sub-clusters

Each significant regulator is assigned a Z score; a positive score (≥2) indicates the regulator is predicted to be activated and a negative score (≤-2) indicates it’s predicted to be inhibited.

(A) Each cluster is highly distinct with cluster-specific regulators and regulators with opposite z-scores from one cluster to another.

(B) Cytokines are activated in Cluster 3.

(C) Growth factors are activated in Cluster 3 but inhibited in Cluster 1.