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. 2022 Apr 23;107(7):1825–1832. doi: 10.1210/clinem/dgac256

Table 2.

Serum levels of 6 protein biomarkers from the first group of participants

Levels of proteins, cps Controls T1D T2D P (T1D vs controls) P (T2D vs controls) P (T1D vs T2D)
OPN 106 ± 32 (× 102) 235 ± 135 (× 102) 134 ± 81 (× 102) 9.382E-7 .66 1.577E-7
IL-1RA 3071 ± 2668 271 ± 269 612 ± 570 1.997E-12 .003 3.362E-9
YKL-40 1299 ± 639 (× 102) 308 ± 139 (× 102) 283 ± 75 (× 102) 4.439E-29 5.677E-18 .81
M-CSF 59 ± 30 20 ± 9 17 ± 8 3.104E-4 3.872E-4 .10
TRAIL 82 ± 38 151 ± 44 142 ± 36 4.461E-45 6.132E-31 .89
SAA 3372 ± 2436 (× 104) 803 ± 3726 (× 104) 1083 ± 3841 (× 104) 1.133E-25 1.846E-18 .04

Abbreviations: cps, counts per second; IL-1RA, interleukin 1 receptor antagonist; M-CSF, macrophage colony-stimulating factor 1; OPN, osteopontin; SAA, serum amyloid A1; T1D, type 1 diabetes; T2D, type 2 diabetes; TRAIL, tumor necrosis factor superfamily member 10; YKL-40, chitinase 3-like 1.